In the original languageTranslation into English
MAIN PROBLEMS IN THE PHARMACEUTICAL DEVELOPMENT AND MANUFACTURE OF DRUGS ON THE BASIS OF IN SITU SYSTEMS
Authors
Bakhrushina E.O
Rubric:Pharmaceutical Sciences
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Annotation
In situ systems are one of the most promising modern delivery systems. Their use in clinical practice can solve the problems of patient compliance, as well as increase the bioavailability of active ingredients, However, the global scientific community needs to make efforts to solve the key problems that stop the development of the technology of these targeted delivery systems.
Keywords
in situ systems
in situ gelling
implants
drug design
target delivery system
Authors
Bakhrushina E.O
Rubric:Pharmaceutical Sciences
534
1
Share
534
1
References:
- Laffleur F, Keckeis V. Advances in drug delivery systems: Work in progress still needed? Int J Pharm X. 2020 Jun 12;2:100050. doi: 10.1016/j.ijpx.2020.100050. Erratum in: Int J Pharm X. 2020 Dec 09;2:100065. PMID: 32577616; PMCID: PMC7305387.
- Vigata M, Meinert C, Hutmacher DW, Bock N. Hydrogels as Drug Delivery Systems: A Review of Current Characterization and Evaluation Techniques. Pharmaceutics. 2020 Dec 7;12(12):1188. doi: 10.3390/pharmaceutics12121188. PMID: 33297493; PMCID: PMC7762425.
- Vigani B, Rossi S, Sandri G, Bonferoni MC, Caramella CM, Ferrari F. Recent Advances in the Development of In Situ Gelling Drug Delivery Systems for Non-Parenteral Administration Routes. Pharmaceutics. 2020 Sep 10;12(9):859. doi: 10.3390/pharmaceutics12090859. PMID: 32927595; PMCID: PMC7559482.
- Kempe S, Mäder K. In situ forming implants - an attractive formulation principle for parenteral depot formulations. J Control Release. 2012 Jul 20;161(2):668-79. doi: 10.1016/j.jconrel.2012.04.016. Epub 2012 Apr 18. PMID: 22543012.
- Bakhrushina E.O., Demina N.B., Shumkova M.M., Rodyuk P.S., Shulikina D.S., Krasnyuk I.I. In situ Intranasal Delivery Systems: Application Prospects and Main Pharmaceutical Aspects of Development (Review). Drug development & registration. 2021;10(4):54-63. https://doi.org/10.33380/2305-2066-2021-10-4-54-63
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