Impact of Disorder and Manufacturing Cost on the Efficacy of Mechano-Bactericidal Nanostructures
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Tina F. Meng
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This work presents a combined mathematical and simulation modeling approach to evaluating the mechano-bactericidal effect of nanostructured surfaces. We show for the first time that a mathematical expression of mechanical stress can be derived from bacterial and nanopillar properties. By applying the model in simulations, we demonstrate that the nanopillar design can be optimized to achieve higher bacteria-killing efficiency. We also show that those high-end fabricating techniques only moderately improve antibacterial efficiency at much higher cost. The study validates the mechano-bactericidal concept, provides a quantitative model for stress, and offers insights for optimizing nanostructure design.
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Authors
Tina F. Meng
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References:
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