SYNTHESIS REACTIONS OF QUINAZOLIN-4-ONE IN THE PRESENCE OF IRON (III)-CHLORIDE CATALYSTS
Authors
Oripov Oybek Bekboyevich, Saitkulov Foziljon Ergashevich, Mirvaliev Zoid Zoxidovich
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Quinazolin-4-one is a significant ring-shaped compound with various biological and pharmacological effects. Iron trichloride (FeCl₃) is being used as a catalyst in making quinazolin-4-one because it works well and is also eco-friendly. FeCl₃, functioning as a Lewis acid, speeds up the closing of the ring by activating centers that attract electrons and helping with the attack of molecules that donate electrons, resulting in faster reactions, better amounts of product, and increased specificity. This paper examines how FeCl₃ helps with creating reactions, particularly by finding the best conditions for the reaction like temperature, solvent, and concentration. The research shows that FeCl₃ can be a useful and environmentally-friendly catalyst for making quinazolin-4-one derivatives, which can be very beneficial for industries and pharmaceutical purposes.
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Authors
Oripov Oybek Bekboyevich, Saitkulov Foziljon Ergashevich, Mirvaliev Zoid Zoxidovich
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References:
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