Evaluation of Cllular and Cytokine Reactions in Patients with Chronic Pancreatitis During Immunotherapy
Authors
Suleymanov Suleyman Fayzullayevich
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The article provides data on the study of cellular parameters of the immune status and cytokine profile in 36 patients with chronic pancreatitis (CP). As a control, 30 apparently healthy individuals who had no pathologies from the gastrointestinal tract were selected. In patients with CP, profound suppression of the main pool of T (CD3) lymphocytes and its subpopulations, and of the interleukin profile were revealed. The use of the immunopreparation Thymoptinum (dose 0.8-1.0 mg per course of therapy) in combination with traditional treatment in patients with CP led to the normalization of the parameters of cellular immunity and stabilization of the interleukin profile.
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Authors
Suleymanov Suleyman Fayzullayevich
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References:
1. Drewes A.M., Stefan A.W. Bouwense S.A.W., Campbell C.M. Guidelines for the understanding and management of pain in chronic pancreatitis // Pancreatolgy. 2017. – Vol. 17. – P. 720–731.
2. Lazarchuk T.B. Dynamics parameters T– and B–links of immunity patients with chronic pancreatictis patients // Bull. of the Sci Ach. – 1999. – № 2. – Р. 76–79. [In Ukrainian].
3. Suleymanov S.F. Immunological processes as etiopathogenesis of chronic pancreatitis // Publishing house: LAP. Saarbrücken, 2015. – 56 p. [In Russian].
4. Suleymanov S.F. Using immucorrection therapy in patients with chronic pancreatitis // European Science Review. – 2016. – № 7–8. – P. 141–142.
5. Suleymanov S.F. Disorders Of The Immune System And Their Immunological Rehabilitation In Patients With Chronic Pancreatitis // Eur. Jour. of Molec. & Clin. Med. – 2020. Vol. 7. – Issue 3.– P. 5178–5187.
6. Suleymanov S.F. Analysis of the degree of immune disorders and the application of immunocorrectors in deseases of digestive system // European Science Review. – Vienna, Austria. –2021. – № 9–10. September–October. – P. 12–15.
7. Suleymanov S.F. Immunological Aspects of Chronic Pancreatitis // Publishing house: "Sadriddin Salim Bukhoriy". - Bukhara, 2022. - 109 p.
8. Suleymanov S.F., Suleymanov F.S. Use of Thymoptinum in Patients with Chro-nic Pancreatitis // Materials of the ІІІ Scientific and Practical International Distance Conference, Kharkiv, March 24, 2023. – P. 166–168.
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