Evaluation of Cllular and Cytokine Reactions in Patients with Chronic Pancreatitis During Immunotherapy
Authors
Suleymanov Suleyman Fayzullayevich
![](/api/crop/media/uploads/journals/journal/Cover_Biomed-2_23.jpg?geometry=280x368)
Share
Annotation
The article provides data on the study of cellular parameters of the immune status and cytokine profile in 36 patients with chronic pancreatitis (CP). As a control, 30 apparently healthy individuals who had no pathologies from the gastrointestinal tract were selected. In patients with CP, profound suppression of the main pool of T (CD3) lymphocytes and its subpopulations, and of the interleukin profile were revealed. The use of the immunopreparation Thymoptinum (dose 0.8-1.0 mg per course of therapy) in combination with traditional treatment in patients with CP led to the normalization of the parameters of cellular immunity and stabilization of the interleukin profile.
Keywords
Authors
Suleymanov Suleyman Fayzullayevich
![](/api/crop/media/uploads/journals/journal/Cover_Biomed-2_23.jpg?geometry=280x368)
Share
References:
1. Drewes A.M., Stefan A.W. Bouwense S.A.W., Campbell C.M. Guidelines for the understanding and management of pain in chronic pancreatitis // Pancreatolgy. 2017. – Vol. 17. – P. 720–731.
2. Lazarchuk T.B. Dynamics parameters T– and B–links of immunity patients with chronic pancreatictis patients // Bull. of the Sci Ach. – 1999. – № 2. – Р. 76–79. [In Ukrainian].
3. Suleymanov S.F. Immunological processes as etiopathogenesis of chronic pancreatitis // Publishing house: LAP. Saarbrücken, 2015. – 56 p. [In Russian].
4. Suleymanov S.F. Using immucorrection therapy in patients with chronic pancreatitis // European Science Review. – 2016. – № 7–8. – P. 141–142.
5. Suleymanov S.F. Disorders Of The Immune System And Their Immunological Rehabilitation In Patients With Chronic Pancreatitis // Eur. Jour. of Molec. & Clin. Med. – 2020. Vol. 7. – Issue 3.– P. 5178–5187.
6. Suleymanov S.F. Analysis of the degree of immune disorders and the application of immunocorrectors in deseases of digestive system // European Science Review. – Vienna, Austria. –2021. – № 9–10. September–October. – P. 12–15.
7. Suleymanov S.F. Immunological Aspects of Chronic Pancreatitis // Publishing house: "Sadriddin Salim Bukhoriy". - Bukhara, 2022. - 109 p.
8. Suleymanov S.F., Suleymanov F.S. Use of Thymoptinum in Patients with Chro-nic Pancreatitis // Materials of the ІІІ Scientific and Practical International Distance Conference, Kharkiv, March 24, 2023. – P. 166–168.