STUDY OF PHYSICO-CHEMICAL PROPERTIES OF BIOMATERIAL OBTAINED BASED ON STRUCTURED COLLAGEN
Authors
Radjabov O.I., Turaev A.S., Otajanov A.Yu., Muydinov N.T., Avezov H.T., Ruzieva M.J., Azimova L.B., Buriev D.A.
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The article presents the results of the study of the physicochemical properties of the biomaterial in the form of a film based on collagen, obtained from the hide of cattle with the preservation of the original fibrous structure, and Na-CMC. The temperature dependence of the rheological properties of collagen, as well as compositions based on collagen and Na-CMC in different mass ratios, was studied. To study the preservation of the three-helix structure of collagen, the dynamic viscosity of aqueous solutions of collagen and compositions based on it were studied at temperatures of 30 and 35ºС. It has been established that at a temperature of 35ºС the native structure of collagen is destroyed. The optimum temperature for the formation of a biomaterial based on an aqueous composition of collagen/polysaccharide in the form of a film is less than 30°C. It is shown that the presence of a plasticizer significantly affects the mechanical properties of the films. When glycerol was added as a plasticizer to aqueous solutions of the collagen/Na-CMC composition, the formation of a highly elastic film was observed. When studying the dissolution time of the experimental samples, it was shown that with an increase in the mass fraction of Na-CMC in the composition of the film, a decrease in swelling and an increase in the dissolution time are observed due to the formation of intermolecular hydrogen bonds between the functional groups of collagen molecules and Na-CMC.
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Authors
Radjabov O.I., Turaev A.S., Otajanov A.Yu., Muydinov N.T., Avezov H.T., Ruzieva M.J., Azimova L.B., Buriev D.A.
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