COMPARATIVE ANALYSIS OF MATERNAL AND PERINATAL OUTCOMES IN PREGNANT WOMEN WITH DELTA AND OMICRON SARS-COV-2 VARIANTS
Authors
Alimova Hilola Pulatovna, Tyan Tatyana Valerievna
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COVID-19 remains a significant global health concern, particularly in pregnant women, who are at increased risk of adverse outcomes. This retrospective single-center cohort study included 9,288 pregnant women with confirmed SARS-CoV-2 infection and compared clinical characteristics and maternal–perinatal outcomes between Delta (n=3,200) and Omicron (n=6,088) variants. The Delta variant was associated with a significantly higher incidence of complications, including uteroplacental insufficiency, acute respiratory distress syndrome, multiple organ dysfunction, preterm birth, and maternal mortality. It also required more frequent intensive care, mechanical ventilation, and cesarean delivery. In contrast, the Omicron variant demonstrated a milder clinical course with significantly higher 30-day survival and lower perinatal mortality. These findings indicate substantial differences in disease severity and outcomes between SARS-CoV-2 variants in pregnancy.
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Authors
Alimova Hilola Pulatovna, Tyan Tatyana Valerievna
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References:
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