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STUDY OF BIOLOGICAL ACTIVITY OF BIOMATERIAL BASED ON STRUCTURED FIBROIN

Authors

Khusenov Arslonnazar, Rakhmanberdiev Gappar, Kiyamova Malika, Usmanov Ravshan, Gulmanov Ilich

Rubric:Chemistry
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Annotation

The article presents information on the significance, hemostatic and biological activity of fibroin-based drugs. The study examined samples of hemostatic biomaterial obtained on the basis of carboxymethylinulin and fibroin, depending on the amount of polymer components of carboxymethylinulin and fibroin. It was found that the carboxymethylinulin/fibroin sample at a mass ratio of 1:0.5 exhibits high hemostatic activity and complete resorption occurs within 21 days.

Keywords

carboxymethylinulin
fibroin
biomaterial
biological activity
hemostatic
resorption.

Authors

Khusenov Arslonnazar, Rakhmanberdiev Gappar, Kiyamova Malika, Usmanov Ravshan, Gulmanov Ilich

References:

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4. Dahlke H., Dociu N., Thurau K. Thrombogenicity Of Different Suture Materials as Revealed by Scanning Electron-Microscopy // J. Biomed Mater Res, 1980, 14(3) Р. 251-268.

5. Babiuc R.D., Purcarea M., Sadagurschi R., Negreanu L. Use of Hemospray in the treatment of patients with acute UGIB-short review // J. Med. Life 2013, 6, P. 117-119.

6. Wang X.X., Liu Q., Sui J.X., Ramakrishna S., Yu M., Zhou Y., Jiang X.Y., Long Y.Z. Recent Advances in Hemostasis at the Nanoscale // Adv. Healthc. Mater. 2019;8:e1900823. doi: 10.1002/adhm.201900823.

7. Barkun A.N., Moosavi S., Martel M. Topical hemostatic agents: A systematic review with particular emphasis on endoscopic application in GI bleeding. Gastrointest. Endosc. 2013., 77. P. 692-700. doi: 10.1016/j.gie.2013.01.020.

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