In the original languageTranslation into English

CONVENIENT SYNTHESIS OF 2-METHYLQUINAZOLIN-4-THIONE BASED ON ANTHRANYL ACID

Authors

Elmuradov Chori Juraevich, Muminova Nigora Kilichovna, Nasimov Khasan Muradovich, Yaxyoeva Maftuna Faxriddin qizi, Saitkulov Foziljon Ergashevich

Annotation

The synthesis of intermediate products based on anthranilic acid, the reactions of excess amides are justified in the article, and optimal synthesis methods of 2-methylquinazolin-4-thione are well studied. The reaction mechanism was proved on the basis of the corresponding spectra.

Keywords

Anthranilic acid
intermediate product
synthon
2-methylquinazolin-4-thione
"structure-activity"
2-methylquinazolin-4-one
N-acetylanthranilic acid
ammonium chloride.

Authors

Elmuradov Chori Juraevich, Muminova Nigora Kilichovna, Nasimov Khasan Muradovich, Yaxyoeva Maftuna Faxriddin qizi, Saitkulov Foziljon Ergashevich

References:

  1. Saitkulov, F. E., Tashniyazov, A. A., Mamadrahimov, A. A., & Shakhidoyatov, K. M. (2014). 2, 3-Dimethylquinazolin-4 (3H)-one. Acta Crystallographica. Section E: Structure Reports Online70(7), o788-o788.
  2. Sapaev, B., Saitkulov, F. E., Tashniyazov, A. A., & Normurodov, O. U. (2021). Study of methylation reactions of 2-phenylquinazoline-4-tion with “soft” and “hard” methylation agents and determination of its biological activity. In E3S Web of Conferences (Vol. 258, p. 04023). EDP Sciences.
  3. Sapaev, B., Sapaev, I. B., Saitkulov, F. E., Tashniyazov, A. A., & Nazaraliev, D. (2022, June). Synthesis of 2-methylquinazoline-4-thione with the purpose of alkylation of 3-propyl 2-methylquinazoline-4-thione with alkylating agents. In AIP Conference Proceedings (Vol. 2432, No. 1). AIP Publishing.
  4. Saitkulov, F., Farhodov, O., Olisheva, M., Saparboyeva, S., & Azimova, U. (2022). Chemical feeding method of lemon plant using leaf stomata. Академические исследования в современной науке1(17), 274-277.
  5. Саиткулов, Ф. Э., Элмурадов, Б. Ж., & Гиясов, К. (2023). Алкилирования хиназолин-4-она «мягким» и «жестким» алкилирующими агентами. Universum: химия и биология, (1-2 (103)), 53-56.
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  7. Saitkulov, F. E., Elmuradov, B. Z., Giyasov, K., Ruziboev, D. M., & Sultonova, S. X. (2023). Efficient synthesis and direction of methylation of 2-methylquinazoline-4 (3h)-thione. Theoretical aspects in the formation of pedagogical sciences2(10), 22-26.
  8. Sapayev, B., Saitkulov, F. E., Normurodov, O. U., Haydarov, G., & Ergashyev, B. (2023). Studying Complex Compounds of Cobalt (II)-Chlooride Gecsacrystolohydrate with Acetamide and Making Refractory Fabrics from Them.

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