In the original languageTranslation into English

STUDYING THE BIOLOGICAL ACTIVITY OF ISOMERIC N-(TOLYL)-α-PICOLINAMIDES IN THE PASS ONLINE PROGRAM

Authors

Abdushukurov Anvar Kabirovich, Yusufov Mukhriddin Saidovich, Burieva Dilnoza Madarttovna

Annotation

The biological activity of the isomers of toluidine and N-(tolyl)-α-picolinamides synthesized on the basis of picolinic acid was studied in the PASS online program [https://www.way2drug.com/PassOnline/index.php]. Indicators of the biological activity of isomeric amides in relation to certain diseases, adverse and toxic effects on the body, negative effects of drugs on the cardiovascular and hepatobiliary systems, cytotoxic effects on cancer cells and human breast cancer cell lines were obtained. The results are summarized in a table. Judging by the tables above, the biological activity of isomeric N-(tolyl)-α-picolinamides showed very similar results compared to each other

Keywords

PASS online program
N-(tolyl)-α-picolinamide
Pa and Pi values
toxicity
cancer cells
prognosis.

Authors

Abdushukurov Anvar Kabirovich, Yusufov Mukhriddin Saidovich, Burieva Dilnoza Madarttovna

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