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STUDY OF PHYSICOCHEMICAL AND TECHNOLOGICAL PROPERTIES OF DRY EXTRACT FROM ROSA RUGOSA LEAVES

Authors

R.M. Khalilov, Wen Juan Xue, Nurbolat Aidarhan, Alimujiang Abulizi, Sh.Sh. Sagdullaev

Rubric:Medical science
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Annotation

At the experimental and technological laboratory of the Institute of Plant Chemistry, a dry extract was obtained from the leaves of Rosa rugosa, containing the flavonoids quercetin-3-O-sophoroside and kaempferol-3-O-sophoroside. To substantiate the composition and technology of solid dosage forms, the physicochemical and technological properties of the dry extract were studied. As a result of experimental studies, the feasibility of incorporating a complex of auxiliary substances into the composition of the solid dosage form and utilizing the method of preliminary wet granulation was determined.

Keywords

dry extract
technological properties.
Rosa rugosa

Authors

R.M. Khalilov, Wen Juan Xue, Nurbolat Aidarhan, Alimujiang Abulizi, Sh.Sh. Sagdullaev

References:

  1. Madrakhimov, Sh.N., Rakhimova, O.R., Khalilov, R.M., Rakhimova, G.R. (2016). Technology of tablets flanorin. Parmaceuticaljournal, 2. 62-65. (in Russ).
  2. Madrakhimov, Sh.N., Rakhimova, O.R., Khalilov, R.M., Kotenko, L.D., Rakhimova, G.R. (2016) Development of the technology and the quality assessment of ferulen tablets. Parmaceuticaljournal, 4. 63-69. (in Uzbek).
  3. Pharmaceutical technology. Solid dosage forms. Textbook (2011). edited by Prof. Kedika, S.A., Moscow. 2011. 661 p. (in Russ).
  4. Nosovitskaya, S.A., Borzunov, E.E., Safiulin, R.M. (1969). Production of tablets. - M.: Medicine, - 136 p. (in Russ).

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