SYNTHESIS OF NITRO-CONTAINING DERIVATIVES BASED ON MODIFIED CARBOXYMETHYLINULIN
Authors
Abdukhamidova Fotima, Khusenov Arslonnazar, Ibragimova Komila, Rakhmanberdiev Gappar
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The development of methods for synthesizing new derivatives of polysaccharides remains one of the most interesting areas in the chemistry of high-molecular-weight compounds. In this regard, research on obtaining nitrogen-containing derivatives of polysaccharides is particularly important. In the presented study, the chemical modification of carboxymethylinulin was carried out through periodate oxidation. This approach enables the selective cleavage of vicinal diol groups with the formation of reactive aldehyde functionalities along the polymer chain. Such structural transformations significantly expand the possibilities for subsequent functionalization and targeted introduction of biologically active fragments. In the next stage, low-molecular-weight heterocyclic compounds containing nitro groups in the structure were chemically immobilized to the macromolecules of the oxidized inulin ester. Reaction conditions affecting the structural properties of the synthesized compounds have been found.
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Authors
Abdukhamidova Fotima, Khusenov Arslonnazar, Ibragimova Komila, Rakhmanberdiev Gappar
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