THE ELEMENTAL CHEMICAL COMPOSITION OF SOME PLANTS OF THE GENUS Heliotropium GROWING IN THE FERGANA VALLEY OF UZBEKISTAN
Authors
Omonova S.S., Matchanov A.D., Khuzhaev V.U., Aripova S.F.

Share
Annotation
The elemental chemical composition of the underground (u/g) and aboveground parts (a/p) of plants of the genus Heliotropium of the Boraginaceae family: H. lasiocarpum Ledeb. and H. dasycarpum Ledeb., growing in the Ferghana Valley of Uzbekistan, has been studied for the first time by inductively coupled argon plasma mass spectrometry (ICP-MS). The data obtained show that 18 out of 21 elements were found in the organs of the studied plants, including 4 macronutrients (Ca, K, Na, Mg), 7 essential trace elements (Co, Cr, Cu, Fe, Mn, Se, Zn), 4 conditionally essential trace elements (Ni, V, As, Li), 3 toxic elements (Pb, Ba, Al). Salts of toxic elements Ag, Be, Cd, and Hg were not detected. It was revealed that of the detected elements in the organs of the studied plants, concentrations of more than 1000 mg/kg contain 3 macronutrients (Ca, K, and Mg), concentrations of 50 to 1000 mg/kg contain 4 elements (Na, Fe, and Zn), and concentrations of 10 to 100 mg/kg contain 1 element. (Mn), ranging from 1-10 mg/kg – 5 elements (Cr, Ni, V, Li, Cu), ranging from 1-5 mg/kg – 2 elements (Se, Co). The composition of trace elements of the body does not decrease the roots of the a/p of H. lasiocarpum are large in Fe (a/p 700,112 mg/kg, u/g 197,725 mg/kg). The composition of the roots and a/p of H. dasycarpum also contains a large proportion of Fe (a/p – 527.441 mg/kg and u/g – 486.441 mg/kg). It was found that A1 accounts for the highest content of toxic elements in plant organs: H. lasiocarpum (355.55 mg/kg and 154.20 mg/kg, respectively) in a/p and H. dasyocarpum (341.44 mg/kg and 276.75 mg/kg, respectively). Salt content of the studied heavy metals of the plant boiler, growing in Uzbekistan, meeting the requirements set by the State Pharmacopoeia XIV of the Russian Federation and WHO.
Keywords
Authors
Omonova S.S., Matchanov A.D., Khuzhaev V.U., Aripova S.F.

Share
References:
1. Heliotropium. Plantarium. Plants and lichens of Russia and neighboring countries: open online gallerie sand plant identification guide. URL: https: //www.plantarium.ru/lang/en/page/ view/ item/ 42844.html.
2. Heliotropium dasycarpum Ledeb. // Plantarium. Plants and lichens of Russia and neighboring countries: open online galleries and plant identification guide. URL: https://www.plantarium.ru/lang/en/page/view/item/18440.html.
3. Vvedensky A.I. The genus Heliotropium. Flora of Uzbekistan, Volume 5. Tashkent: Publishing House of the Academy of Sciences of the Uzbek SSR. 1961. P. 668.
4. Yunusov S.Y. Handbook of Alkaloids, Ed. Academy of Sciences of the Uzbek SSR. Tashkent, 1981. P. 312-313.
5. Shakirov R., Vinogradova V.I., Aripova S.F., Sultankhodzhaev M.N., Bessonova I.A., Akhmedzhanova V.I., Tulaganov T.S., Salimov B.T. Natural Compounds: Plant, Sources, Structure and Properties, Springer. New York. 2013. Рр. 16-18 http://www.springer.com/us/book/9780387491394.
6. Kakar F., Akbarian Z., Leslie T., Laice M., Watson D., Van Hans E., Fahim O., Mofle D. // Journal of Toxicology. 2010: 1–7. DOI:10.1155/2010/313280.
7. Chuanhui Ma, Yang Liu, Lin Zhu, Hong Ji, Xun Song. Determination and regulation of hepatotoxic pyrrolizidine alkaloids in food: A critical review of recent research (англ.) // Food and Chemical Toxicology. 2018-09-01. Vol. 119, Pр. 50–60. ISSN 0278-6915. doi:10.1016/j.fct.2018.05.037.
8. Xia Q., Yan J., Chou M.W., Fu P.P. Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine // Toxicology letters. 2008, V. 178. № 2. Pр. 77-82.
9. S.S. Omonova, V.U. Khuzhaev, S.F. Aripova, ALKALOID CONTENT IN PLANTS OF THE GENUS Heliotropium GROWING IN THE FERGHANA VALLEY OF UZBEKISTAN, Materials of the Scientific and practical conference "Actual problems of chemistry of natural compounds", Tashkent, April 19, 2025. p. 58.
10. Sh. Kh. Rakhimova, L. G. Mezhlumyan, S. S. Omonova, A. A. Azamatov, S. F. Aripova, F. S. Nabieva, INVESTIGATION OF THE PROTEIN COMPONENTS OF THE ABOVEGROUND PART OF THE HELIOTROPIUM LASIOCARPUM PLANT AND ITS BIOLOGICAL ACTIVITY. Materials of the Scientific and practical conference "Actual problems of chemistry of natural compounds", Tashkent, April 19, 2025. p. 185.
11. S.S. Omonova, O.D. Matchanov, R.S. Khasanov, S.F. Aripova. Study of the content of flavonoids and vitamins in plants of the genus Heliotropium growing in Uzbekistan, Uzbek Biological Journal, 2024, No. 5, pp. 10-13.
12. Oberlis D., Harland B., Skalny A. The biological role of macro- and microelements in humans and animals, Orenburg, 2018. Р. 658.
13. OFS.1.1.0013.15. Statistical processing of the results of a chemical experiment // State Pharmacopoeia of the Russian Federation, XIV ed., Moscow, 2018. Vol. 1. Pp. 289-318.
14. Polyanskaya I.S. A new classification of bioelements in bioelementology // Dairy and Economic Bulletin, 2014. No. 1. Pp. 34-42.
15. Lysikov Yu.A. Macro- and microelements in the human body: functions, deficit/surplus // Specialist's Handbook Magazine. 2008, No. 20. Р. 262.
16. Kolomiytseva M.G., Gabovich R.D. Microelements in medicine. Monograph, M. Medicine. 1970. Р. 288.
17. Greer F. R., Krebs NF, American Academy of Pediatrics Committee on Nutrition. Optimizing bone health and calcium intakes of infants, children, and adolescents (англ.) // Pediatrics: journal, American Academy of Pediatrics. 2006, Vol. 117. № 2. P. 578-585. PMID 16452385.
18. Hatfield, D. L.; Gladyshev, V. N. How Selenium Has Altered Our Understanding of the Genetic Code (англ.) // Molecular and Cellular Biology : Journal. 2002. Vol. 22, № 11. Pp. 3565-3576. doi:10.1128/MCB.22.11.3565-3576.2002. PMID 11997494. PMC 133838.
19. Struyev I. V., Simakhov R. V. Selenium, its effect on the body and its use in medicine // Collection of scientific papers "Natural Sciences and humanism". Edited by Professor, Doctor of Biological Sciences N. N. Ilyinsky, 3(2). 2006. Pp. 127-136.
20. Idelson L.I., Vorobyev A.I. Iron deficiency anemia. Guide to Hematology. Edited by A.I. Vorobyov in 3 volumes. Newdiamed. 2005. Р. 123.
21. Tivo P.V., Bytko I.G. Heavy metals and Ecology, 1996. Minsk. Unipol, Р. 191.
22. OFS 1.5.3.0009.15. Determination of the content of heavy metals and arsenic in medicinal plant raw materials and medicinal herbal preparations // State Pharmacopoeia of the Russian Federation. XIII ed. Moscow, 2015. Vol. 2. Pp. 421-433.
23. World Health Organization et al. National policy on traditional medicine and regulation of herbal medicines: Report of a WHO global survey. Geneva. 2005. P. 168; ОФС.1.1.0009. 4579.1.
