STUDY OF BENZYLATION REACTIONS OF QUINAZOLIN-4-ONE IN THE PRESENCE OF VARIOUS SOLVENTS
Authors
Zulpanov Fazliddin Abduxakimovich, Saitkulov Foziljon Ergashevich, Elmuradov Burxon Jurayevich, Arzanov Ravshan Xurramovich
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Annotation
In order to improve reaction conditions and product yields, this study examines quinazolin-4-one's benzylation reactions using different solvents. An essential scaffold for the production of bioactive compounds is quinazolin-4-one, a substance with notable pharmacological activity such as anti-inflammatory, anticancer, and antibacterial qualities. Quinazolin-4-one's biological potential can be enhanced and structural variety introduced via benzylation. The effects of several solvents on reaction kinetics, selectivity, and overall efficiency were investigated. The results show how different solvents affect the reaction's process, providing important information for choosing the best solvents to increase yields and regulate product production. This work advances the creation of more effective synthesis processes for quinazolin-4-one derivatives with specific characteristics.
Keywords
Authors
Zulpanov Fazliddin Abduxakimovich, Saitkulov Foziljon Ergashevich, Elmuradov Burxon Jurayevich, Arzanov Ravshan Xurramovich
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References:
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