Determination of the effective dose of "sumakh fruit extract" in correcting the genotoxicity of chemicals in an artificially induced mutation process
Authors
Guliyev Mahir, Israfilova Sabina, Huseynova Shahla, Guliyeva Nigar
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This study explores the antimutagenic properties of sumakh fruit extract against the mutagen 4-nitroquinoline-1-oxide (4NQO) using human peripheral blood lymphocytes. The extract was tested in doses ranging from 0.001 to 10 μg/ml. Results showed that sumakh fruit extract significantly reduced sister chromatid exchanges, a marker of DNA damage, with optimal protection observed at 0.01 μg/ml. These findings highlight the extract's potential as a protective agent against mutagenic damage.
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Authors
Guliyev Mahir, Israfilova Sabina, Huseynova Shahla, Guliyeva Nigar
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References:
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Muhammad Mushtaq, Bushra Sultana, Farooq Anwar, Sidra Batool. Antimutagenic and Antioxidant po- tential of aqueous and acidified methanol extracts from citrus limonum fruit residues // J. Chil. Chem. Soc., – No. 2. 2015.
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