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CLINICAL AND PATHOLOGICAL SPECIFICS AND RESPONSE TO TREATMENT OF RARE HISTOLOGICAL FORMS OF BREAST CANCER

Authors

Kahharov А.J., Djumaniyazova G.M.

Rubric:Medical science
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Annotation

The purpose of the study is to study the features of the clinical course, characteristics and response to treatment of rare histological forms of breast cancer.

 

Methods: The study included 102 patients with rare forms of breast cancer and a control group of 54 patients with invasive ductal cancer. Analysis of histological subtypes was performed, as well as evaluation of clinical and pathological parameters. Statistical methods were used to compare survival and other key metrics between groups.

Results: The study revealed statistically significant differences in age, histological grade, tumor size, lymph node incidence and incidence of stage IV de novo between patients with rare histological forms of breast cancer and standard invasive ductal carcinoma. In addition, differences in response to therapy have been found among different subtypes of these rare forms

Conclusions: Rare histological forms of breast cancer exhibit unique clinicopathological features and disease behavior, which may influence treatment strategy and prognosis. The results highlight the importance of an individualized approach to the diagnosis and treatment of these patients, as well as the need for in-depth stratification to improve therapeutic outcomes and quality of life.

Keywords

rare histological forms
clinicopathological features
survival
breast cancer
individualized treatment.

Authors

Kahharov А.J., Djumaniyazova G.M.

References:

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  7. Dieci MV, Orvieto E, Dominici M, Conte P, Guarneri V. Rare breast cancer subtypes: histological, molecular, and clinical peculiarities. Oncologist. 2014 Aug;19(8):805-13. doi: 10.1634/theoncologist.2014-0108. Epub 2014 Jun 26. PMID: 24969162; PMCID: PMC4122475.
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