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European Science Review, Issue 1-2/2017

The degree of production cytokines il‑8 and il‑12 in patients with extrinsic allergic alveolitis

DOI: https://doi.org/10.29013/ESR-17-1.2-108-110

Pages: 108 - 110

Authors: Rakhimov M. M., Aralov N. R., Akhmedov F. S., Ziyadullaev S. K., Dushanova G. A.

Abstract: The objective of the research was to examine the level of concentration of certain cytokines, involved in the regulation of immune response in patients with extrinsic allergic alveolitis (EAA), in particular production IL‑8 and IL‑12. To clarify the immunological bases of the pathogenesis EAA we studied the concentration of certain cytokines involved in the regulation of immune response in patients EAA in particular IL‑8 production and IL‑12. Analysis of the content of IL‑8 in the surveyed patients EAA showed that the level of it’s in the general group of patients studied was 38.4±2.5 pg/ml and greatly exceeds the values characteristic for healthy persons (18.1±1.8 pg/ml, p<0.01). Thus, the highest level studied parameter seen in the patients of chronic stage EAA that distinguishes this group among the total group studied patients with EAA, and distinguishes it from the two comparison groups with acute and subacute stage of the disease

Keywords: Extrinsic allergic alveolitis, cytokines, immune response

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