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European Science Review, Issue 9-10/2016

Study on effect of α-lipoic acid on phospholipid composition of rat cardiac tissue under hypobaric hypoxia

DOI: https://doi.org/10.29013/ESR-16-9.10-13-16

Pages: 13 - 16

Authors: Mamadaliyeva N. I., Saatov T. S., Umerov O. I.

Abstract: Hypoxia is a rather frequent pathological or borderline state caused by the reduction of oxygen concentrations in the ambient environment or dysmetabolism of oxygen in an organism. The simulated chronic hypoxia similar to the one at the altitude of 7,000 m, caused changes in total sum of phospholipids in rat cardiac tissue and proportions of some phospholipids. Pharmacocorrection of the changes with berlithion containing α-lipoic acid was found to normalize levels of some rat cardiac tissue phospholipids.

Keywords: cardiac tissue, hypobaric hypoxia, phospholipid

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